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Table 5 Circulatory support and postoperative outcome related to incremental quartiles of NT-proBNP on POD3

From: Utility of NT-proBNP as an objective marker of postoperative heart failure after coronary artery bypass surgery: a prospective observational study

 

NT-proBNP POD3< 2167 (n = 81)

NT-proBNP POD3≥2167 to <3610(n = 81)

NT-proBNP POD3≥3610 to <6010 (n = 81)

NT-proBNP POD3≥6010 (n = 82)

p value

PHF

4% (3)

6% (5)

6% (5)

21% (17)

0.001

Severe PHF

1% (1)

0

0

6%(5)

0.01

Use of Inotrope

11% (9)

22% (18)

23% (19)

39% (32)

0.001

Use of IABP

0

0

0

2% (2)

0.11

Duration of inotropic treatmenta (h)

3.2 ± 16.9

7.2 ± 25.7

6.0 ± 14.9

18.7 ± 41.9

0.004

Duration of inotropic treatment b(h)

29.2 ± 44.8

32.6 ± 47.3

25.5 ± 21.3

47.9 ± 56.1

0.61

Duration of inotropic treatment > 24 h

2% (2)

6% (5)

9% (7)

20% (16)

0.001

More than one Inotrope at the same time

4% (3)

2% (2)

4% (3)

11% (9)

0.06

Adrenalin used

11% (9)

19% (15)

21% (17)

32% (26)

0.011

Milrinone used

5% (4)

7% (6)

7% (6)

19% (15)

0.016

Levosimendan used

1% (1)

0

1% (1)

6% (5)

0.035

Troponin T POD3 (ng/L)

180 [100–295]

210 [120–370]

250 [130–455]

490 [230–750]

< 0.0001

Delta Troponin T POD3-Pre (ng/L)

135 [35-220]

190 [100-355]

170 [90-340]

390 [175-600]

< 0.0001

ICU stay (h)

18.2 ± 11.3

30.4 ± 55.7

22.5 ± 15.6

48.7 ± 88.6

< 0.0001

ICU stay > 72 h

1% (1)

5% (4)

2% (2)

11% (9)

0.02

Ventilation time (h)

4.0 ± 5.3

12.3 ± 52.2

5.1 ± 5.0

25.9 ± 81.4

< 0.0001

Ventilation time > 48 h

1% (1)

2% (2)

0

9% (7)

0.008

AKI

9% (7)

10% (8)

6% (5)

32% (26)

< 0.0001

Postoperative stroke

0

1% (1)

0

4%(3)

0.11

Hospital mortality

0

0

0

5% (4)

0.007

  1. Data given as medians [interquartile range], percentages (number), or means ± standard deviation. aAverage duration of inotropic treatment including all patients. bAverage duration of inotropic treatment in those receiving inotropic treatment. AKI acute kidney injury, CK-MB creatine kinase-MB isoenzyme, ICU intensive care unit, POD postoperative day