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Table 4 Circulatory support and postoperative outcome related to incremental quartiles of NT-proBNP on POD1

From: Utility of NT-proBNP as an objective marker of postoperative heart failure after coronary artery bypass surgery: a prospective observational study

 

NT-proBNP POD1 < 1324 ng/L (n = 80)

NT-proBNP POD1 ≥ 1324 ng/L to < 2065 ng/L (n = 80)

NT-proBNP POD1 ≥ 2065 ng/L to < 3650 ng/L (n = 80)

NT-proBNP POD1 ≥ 3650 ng/L (n = 80)

p value

PHF

1% (1)

11% (9)

8% (6)

19% (15)

0.002

Severe PHF

0

0

3% (2)

6% (5)

0.02

Use of Inotrope

10% (8)

20% (16)

23% (18)

43% (34)

< 0.0001

Use of IABP

0

0

1% (1)

1% (1)

0.57

Duration of inotropic treatment a(h)

1.0 ± 3.9

6.3 ± 20.4

9.0 ± 26.4

19.1 ± 42.5

< 0.0001

Duration of inotropic treatment b(h)

10.1 ± 8.1

31.6 ± 36.6

39.9 ± 44.0

44.9 ± 56.0

0.21

Duration of inotropic treatment > 24 h

0

6% (5)

11% (9)

20% (16)

< 0.0001

More than one Inotrope at the same time

1% (1)

3% (2)

5% (4)

10% (8)

0.045

Adrenalin used

9% (7)

18% (14)

21% (17)

33% (26)

0.002

Milrinone used

4% (3)

8% (6)

8% (6)

28% (14)

0.016

Levosimendan used

0

0

1% (1)

5% (4)

0.031

Troponin T POD3 (ng/L)

180 [110–280]

250 [140–355]

220 [130–600]

450 [200–725]

< 0.0001

Delta Troponin T POD3-Pre (ng/L)

140 [58–230]

190 [110–350]

170 [80–430]

300 [135–520]

0.001

ICU stay (h)

19.1 ± 10.5

22.8 ± 16.7

23.5 ± 21.5

53.1 ± 101.1

0.002

ICU stay > 72 h

0

4% (3)

3% (2)

13% (10)

0.001

Ventilation time (h)

4.4 ± 4.5

5.3 ± 5.9

6.7 ± 18.1

28.9 ± 93.2

0.001

Ventilation time > 48 h

0

0

1% (1)

10% (8)

< 0.0001

AKI

8% (6)

4% (3)

13% (10)

30% (24)

< 0.0001

Postoperative stroke

1% (1)

0

1% (1)

1% (1)

0.8

Hospital mortality

0

0

3% (2)

4% (3)

0.14

  1. Data given as medians [interquartile range], percentages (number) or means ± standard deviation. aAverage duration of inotropic treatment including all patients. bAverage duration of inotropic treatment in those receiving inotropic treatment. AKI acute kidney injury, CK-MB creatine kinase-MB isoenzyme, ICU intensive care unit, POD postoperative day