|
Variables
|
All patients (n = 382)
|
Without PHF (n = 347)
|
PHF (n = 35)
|
p valuea
|
Severe PHF (n = 7)
|
p valueb
|
|---|
|
Age (years)
|
69 [62–75]
|
68 [62–75]
|
73 [68–78]
|
0.004
|
75 [72–78]
|
0.035
|
|
Female gender
|
19% (73)
|
19% (66)
|
20% (7)
|
0.82
|
29% (2)
|
0.62
|
|
BMI (kg/m2)
|
27 [24–30]
|
27 [24–29]
|
28 [24–31]
|
0.39
|
30 [23–31]
|
0.78
|
|
EuroSCORE II
|
2.4 [1.6–3.9]
|
2.3 [1.6–3.8]
|
3.8 [2.6–6.1]
|
< 0.0001
|
9.0 [4.2–11.1]
|
0.001
|
|
Diabetes
|
24% (91)
|
23% (79)
|
34% (12)
|
0.15
|
57% (4)
|
0.06
|
|
Hypertension
|
61% (231)
|
60% (207)
|
69% (24)
|
0.37
|
100% (7)
|
0.046
|
|
COPD
|
7% (26)
|
6% (21)
|
14% (5)
|
0.08
|
14% (1)
|
0.37
|
|
Hemoglobin (g/L)
|
137 ± 14
|
137 ± 13
|
133 ± 14
|
0.11
|
121 ± 11
|
0.002
|
|
Troponin T (ng/L)
|
0 [0–60]
|
0 [0–50]
|
30 [0–180]
|
0.13
|
220 [30–450]
|
0.019
|
|
p-Creatinine (μmol/L)
|
91 [80–104]
|
90 [79–104]
|
96 [86–115]
|
0.016
|
100 [95–147]
|
0.09
|
|
eGFR (mL min−1 • 1.73 m−2)
|
76 [58–97]
|
77 [59–97]
|
67 [47–84]
|
0.023
|
56 [40–79]
|
0.12
|
|
NT-proBNP (ng/L)
|
420 [150–970]
|
380 [140–864]
|
900 [410–1730]
|
< 0.0001
|
1920 [1030–4202]
|
0.001
|
|
Cerebrovascular disease
|
8% (32)
|
9% (30)
|
6% (2)
|
0.75
|
0
|
1
|
|
Three-vessel disease
|
77% (293)
|
75% (260)
|
94% (33)
|
0.01
|
100% (7)
|
0.2
|
|
Left main stenosis
|
36% (138)
|
35% (121)
|
48% (17)
|
0.14
|
57% (4)
|
0.25
|
|
AMI < 3 weeks
|
65% (249)
|
63% (220)
|
83% (29)
|
1
|
86% (6)
|
0.43
|
|
History of AMI
|
73% (278)
|
71% (247)
|
89% (31)
|
0.028
|
86% (6)
|
0.68
|
|
CCS IV
|
60% (230)
|
60% (207)
|
66% (23)
|
0.59
|
86% (6)
|
0.25
|
|
Angina at rest < 48 h
|
17% (61)
|
16% (53)
|
24 (8)
|
0.33
|
43% (3)
|
0.09
|
|
Moderate LV dysfunction
|
12% (47)
|
11% (39)
|
23% (8)
|
0.06
|
43% (3)
|
0.039
|
|
Severe LV dysfunction
|
4% (14)
|
3% (9)
|
14% (5)
|
0.005
|
43% (3)
|
0.001
|
- Data given as medians [interquartile range], percentages (number)
- AMI < 3 weeks acute myocardial infarction within 3 weeks of surgery, Angina at rest < 48 h angina at rest within the last 48 h before surgery, BMI body mass index, CCS IV Canadian Cardiovascular Society, COPD chronic obstructive pulmonary disease, eGFR estimated glomerular filtration rate according to MDRD formula, EuroSCORE II European system for cardiac operative risk evaluation II, LV left ventricular
- ap for without PHF vs. PHF
- bp for without PHF vs. severe PHF