Skip to main content

Table 1 Summary of included randomized controlled trials

From: The effect of systemic lidocaine on post-operative opioid consumption in ambulatory surgical patients: a meta-analysis of randomized controlled trials

Author

Year

Procedure

Number treatment/control

Intervention/control

Infusion duration

Type of anesthesia

Adverse events

De Oliveira et al. (De Oliveira et al., 2012)

2012

Gynecological laparoscopy

35/35

1.5 mg/kg lidocaine bolus with 2 mg/kg/h infusion

0.9% normal saline

End of surgery

Sevoflurane

None

Dewinter et al. (Dewinter et al., 2016)

2016

Laparoscopic sterilization

39/40

1.5 mg/kg lidocaine bolus with 1.5 mg/kg/h infusion

0.9% normal saline

30 min after surgery

Sevoflurane

None

Lauwick et al. (Lauwick et al., 2008)

2008

Laparoscopic cholecystectomy

25/24

1.5 mg/kg lidocaine bolus with 1.5 mg/kg/h infusion

0.9% normal saline

End of surgery

Desflurane

(1) Persistent hypertension, (1) rapid atrial fibrillation

McKay et al. (McKay et al., 2009)

2009

Laparoscopic endocrine/breast/gynecology/minor orthopedic

29/27

1.5 mg/kg lidocaine bolus with 2 mg/kg/h infusion

1.5 mg/kg lidocaine bolus

0.9% normal saline infusion

60 min after surgery

Sevoflurane

Desflurane

Isoflurane

(1) Dizziness and visual disturbances

Ortiz et al. (Ortiz et al., 2016)

2016

Laparoscopic cholecystectomy

21/22

1.5 mg/kg lidocaine bolus with 3 mg/kg/h infusion

0.9% normal saline infusion

60 min after surgery

Isoflurane

None