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Table 2 A list of causes of hypochloremia

From: Clinical physiology aspects of chloremia in fluid therapy: a systematic review

Mechanism Site of action Example
Loss of chlorides Gastrointestinal tract Vomiting
Gastric drainage
Ileostomy with high waste products elimination rates
  Kidney Diuretics
Bartter’s syndrome
Gitelman’s syndrome
Excess intake of water (relative to chlorides) Congestive heart failure Hypotonic solution infusion
  SIADH  
Excess sodium intake (relative to chlorides)   NaHCO3 infusion
  1. SIADH the syndrome of inappropriate antidiuretic hormone secretion, NaHCO3 sodium bicarbonate. Adapted from Bandak G, Kashani KB. Chloride in intensive care units: a key electrolyte. F1000Res. 2017; 6:1930