Table 4 Intraoperative fluid balance. The effect was presented as a mean difference in goal-directed haemodynamic group in comparison with controls. CI confidence interval, IV inverse variance
Outcome | No. of studies | No. of patients | Analysis | Effect (95% CI) | P value |
|---|---|---|---|---|---|
Intra-operative crystalloids | 42 | 4956 | Mean difference (IV, random) | −375 (−581 to −170) | P = 0.0003 |
Intra-operative colloids | 42 | 4984 | Mean difference (IV, random) | 281 (166 to 396) | P < 0.00001 |
Cumulative intra-operative fluid input | 27 | 2907 | Mean difference (IV, random) | −212 (−254 to 171) | P < 0.00001 |