Table 3 Peri-operative patient characteristics split according to whether they fulfilled criteria for vasoplegia, or not
No vasoplegia, median IQR (n = 259) | Vasoplegia, median IQR (n = 61) | p value | |
|---|---|---|---|
Pre-op | |||
Age (years) | 66 (55.25–74) | 70 (58–77) | 0.209 |
Weight (kg) | 70 (60–83) | 61 (54.5–70) | <0.001 |
Pre-op Hb (g/l) | 124 (111–134.75) | 119 (104–131) | 0.053 |
Pre-op albumin (g/l) | 42 (39–44) | 42 (39.25–44) | 0.433 |
Pre-op chemotherapy no. (%) | 78 (37%) | 20 (39%) | 0.872 |
P-POSSUM mortality | 4.85(1.7–13.2) | 16.9 (7.0–23.6) | <0.001 |
P-POSSUM morbidity | 70.9 (37.0–88.7) | 92.4 (80.2–95.3) | <0.001 |
Intra-op | |||
IV fluid given (ml) | 2000 (1275–3000) | 3500 (2500–4650) | <0.001 |
Blood transfusion (ml) | 0 (0–0) | 0 (0–268.5) | 0.019 |
Surgical_EBL (ml) | 600 (300; 1200) | 1450 (925–2000) | <0.001 |
Post-op | |||
Cumulative fluid balance (ml) | 2760 (1572–4186) | 4675 (1854–6549) | 0.001 |
Hb on POD1 (g/l) | 108 (99–118) | 111 (100.5–118) | 0.396 |
Hb drop (g/l) | 17 (6–24.8) | 9 (− 7–21) | 0.01 |
Albumin POD1 (g/l) | 29.5 (26–32) | 27 (23–30) | <0.001 |
Albumin drop (g/l) | 13 (9–15) | 13 (11–17.8) | 0.046 |
CRP POD1 (mg/l) | 61 (40–95) | 93 (48.5–131) | 0.002 |
Epidural use, no. (%) | 179 (69%) | 50 (82%) | 0.058 |
ICU LOS (days) | 1.9 (1.05–2.88) | 2.94 (2.22–3.88) | <0.001 |
Hospital LOS (days) | 5.08 (4.01–6.49) | 6.8 (5.78–8.17) | <0.001 |
Mortality at 1 year, no. (%) | 10 (5%) | 4 (8%) | 0.485 |