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Table 4 Results of multivariate regression analysis—primary outcomes

From: Using provider-focused education toolkits can aid enhanced recovery programs to further reduce patient exposure to opioids

 

Estimate compared to pre-implementation year*

95% confidence limits

p value

Intraoperative OME

− 15 milliequivalents

− 10.3 to − 19.9

< 0.0001

0–12 h postop OME

5.1 milliequivalents

− 28 to 38.6

0.76

12–24 h postop OME

− 29.5 milliequivalents

− 62.6 to 3.5

0.08

24-36 h postop OME

− 22.8 milliequivalents

− 43 to − 2.4

0.03

Total OME day before discharge

− 18 milliequivalents

− 5.7 to − 31

0.005

Total OME day of discharge

− 9.9 milliequivalents

− 16 to − 3.5

0.003

  1. OME oral morphine equivalents
  2. *Covariate of interest was post-implementation year (compared with pre-implementation year). Models accounted for age, gender, service line, American Society of Anesthesiologist (ASA) rating, opioid use at the time of admission (including methadone), surgical approach (minimally invasive vs open), case mix index, epidural use, and multimodal analgesic