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Table 3 Univariate and multivariate linear regression of factors associated with change in haemoglobin (Δ Hb mg/L) following intravenous iron infusion prior to elective colorectal surgery for cancer (n = 47)

From: The impact of preoperative systemic inflammation on the efficacy of intravenous iron infusion to correct anaemia prior to surgery for colorectal cancer

Characteristic

Univariate regression coefficient (95% CI)

p

Multivariate regression coefficient (95% CI)

p

Male sex

− 7.7 (− 17.3 to 1.9)

0.112

Age

4.7 (− 1.6 to 10.9)

0.140

ASA

2.0 (− 5.6 to 9.7)

0.594

TNM stage

8.2 (2.2–14.2)

0.008

0.780

Tumour site

1.8 (− 4.9 to 8.6)

0.590

Total iron dose (mg)

0.02 (0.01–0.03)

0.003

0.01 (0.0–0.2)

0.034

Days from infusion to surgery

0.5 (0.3–0.7)

< 0.001

0.4 (0.2–0.6)

< 0.001

Pre-iron infusion Hb (mg/L)

− 0.8 (− 1.1 to − 0.6)

< 0.001

− 0.5 (− 0.7 to − 0.2)

0.002

Pre-iron infusion CRP and ferritin group

− 6.9 (− 11.50 to − 2.19)

0.005

− 4.7 (− 7.9 to − 1.47)

0.006

  1. AOI anaemia of inflammation, ASA American Society of Anesthesiology, CRP C-reactive protein (mg/L), Fer ferritin (μg/L), FID functional iron deficiency, Hb haemoglobin (g/L), IDA iron deficiency anaemia, IV intravenous, POD postoperative day