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Table 2 Classification of cannabinoids and some commercially available preparation

From: Cannabis-based medicines and the perioperative physician

GroupWhere foundMajor known CompoundsSubstance found inTrade nameRoute of administrationCurrent uses
Endo
-cannibinoid
Endogenous within body-Arachidonoyl ethanolamide (Anandamide)
-2-arachidonylglycerol (2-AG)
-Docosatetraenoyl-ethanolamide (DEA),
-N-arachidonyldopamine (NADA),
-Virodhamine,
-2-arachidonylglyceryl,
-noladin ether
-dihomo- gamma-linolenoylethanolamide (HEA).
    
Synthetic cannabinoidsChemically synthesisedSynthetic THC
-(-) trans isomer of delta 9 THC
DronabinolMarinol®Oral capsule (formulated in sesame oil)US; FDA approved;
-anorexia associated weight loss in AIDS patients
-chemo induced nausea and vomiting *
UK; not available
Syndros®Liquid formulationUS; FDA approved
- anorexia associated weight loss in AIDS patients
-chemo induced nausea and vomiting *
Synthetic THC analogue (single molecule)NabiloneCesamet®Oral capsuleUS; FDA approved chemo induced nausea and vomiting
UK; -chemo induced nausea and vomiting *
Variety; mainly aminoalkylindole derivatives ie JWH-018, UR-144, PB-22Legal highsSpice, K2, eclipseOral Smoked 
Phyto
-cannibinoid (plant derived)
Cannabis genus;
-cannabis sativa,
-cannbis indica
-cannabis ruderalis
THC content varies 1-22%
CBD content varies 0.05-9%
Cannabis; Marijuana Inhalation (commonly smoked)UK; Illegal
US; legalised for medical use in 29 states, recreational use in 9 states
THC content varies 1-22%
CBD content varies 0.05-9%
Cananbis; Hashish OralUK; Illegal
US; legalised for medical use in 29 states, recreational use in 9 states
Pure CBD (no psychoactive properties)Cannabidiol Oral capsule
Oromucosal spray
 
EpidiolexOilUS;FDA approved for treatment resistant epilepsy
2.7mg THC and 2.5mg CBD per sprayNabiximolsSativex®Oromucosal sprayUS; not approved. Approved in 30 other coutnrie
UK; MHRA but not NICE approved. MS induced spasticity
2.5mg THC, 1.25mg CBDCannador Oral capsuleGerman based research only
  1. *not responded to conventional antiemetics