Table 1 Trial characteristics of cardiac rehabilitation exercise trials
Author, year | Patient characteristics | Type of NP | Baseline NP in intervention group (pg/ml) |
|---|---|---|---|
Kobayashi et al. 2003 | Stable NYHA II-III. EF < 40% | BNP | 281 ± 92 |
Meyer et al. 2004 | Stable NYHAII-III. EF ≤ 40% | NT-proBNP | 1092 ± 980 |
Jonsdottir et al. 2006 | Patients previously hospitalised in past 3 years for heart failure | BNP | 173.2 ± 180.4 |
Maria Sarullo et al. 2006 | Stable CHF. EF < 40% | NT-proBNP | 3376 pg/ml ± 3133 |
Brubaker et al. 2009 | CHF. EF ≤ 45% | BNP | 176 ± 38 |
Malfatto et al. 2009 | Chronic heart failure | BNP | 293 ± 115 |
Parrinello et al. 2010 | Stable NYHAII-III. EF ≤ 45% | BNP | 205.2 ± 46.5 |
Gary et al. 2011 | Stable NYHA II-III, stable on medical therapy. EF 15 to 40% | BNP | 184.4_151.6 |
Guazzi et al. 2012 | Stable NYHA class II or III, stable on medical therapy. EF ≤ 45% | NT-proBNP | 1088.1 ± 447.1 |
Norman et al. 2012 | Volunteers, NYHAII-IV, ≥ 21 years, LVEF ≤ 40%, on optimal medical therapy | BNP | 1088.1 ± 447.1 |
Sandri et al. 2012 | Stable CHF. EF < 40% | NT-proBNP | ≤ 55 years, 1675 ± 354 ≥ 65 years, 1301 ± 261 |
Eleuteri et al. 2013 | Stable NYHA II, stable on medical therapy. EF ≤ 40% | NT-proBNP | 1570.7 ± 3125.8 |
Ahmad et al. 2014, HF-ACTION substudy | CHF patients with reduced left ventricular ejection fraction (< 35%) | NT-proBNP | 960.6 ± 1114 |
Aksoy et al. 2015 | NYHAII-III CHF on optimal medical therapy. EF 35 to 55% | NT-proBNP | Continuous aerobic exercise group 20.79 ± 12.8 Interval exercise group 24.00 ± 18.27 |