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Table 4 Intraoperative management

From: Impact of an enhanced recovery pathway on length of stay and complications in elective radical cystectomy: a before and after cohort study

 

Historical controls (N = 100)

ERAS patient (N = 100)

p value

ERAS pathway compliance

 Preoperative oral carbohydrate drink

0 (0.00%)

87 (87.00%)

< 0.0011

  Unknown

0 (0.00%)

10 (10.00%)

 

 Antibiotic prophylaxis in the OR

98 (98.00%)

100 (100.00%)

0.4971

 Thrombosis prophylaxis

62 (62.00%)

97 (97.00%)

< 0.0011

 Epidural placed

74 (74.00%)

95 (95.00%)

< 0.0011

 Any intraoperative block

4 (4.00%)

2 (2.00%)

0.6831

 PONV prophylaxis administered

80 (80.00%)

98 (98.00%)

< 0.0011

 Number of PONV prophylaxis medications given

0.81 (0.46)

1.37 (0.54)

< 0.0012

 Upper-body forced-air heating cover used

99 (99.00%)

99 (99.00%)

1.0001

 Hemodynamic monitor

13 (13.00%)

99 (99.00%)

< 0.0011

  Unknown

11 (11.00%)

0 (0.00%)

 

 Nasogastric tube used postoperatively

55 (55.00%)

30 (30.00%)

< 0.0013

 Parenteral opioids given within 48 h postoperatively

32 (32.00%)

39 (39.00%)

0.3013

Fluids

 Intraoperative blood loss (mL)

1411.25 (901.84)

999.25 (549.87)

0.0012

 RBC transfusion

80 (80.00%)

48 (48.00%)

< 0.0013

  RBC transfusion amount (mL)

945.47 (917.51)

408.26 (544.82)

< 0.0012

 FFP transfusion

27 (27.00%)

9 (9.09%)

0.0013

  FFP transfusion amount (mL)

152.43 (322.96)

47.60 (167.12)

0.0012

 Cryoprecipitate transfusion

4 (4.00%)

3 (3.00%)

0.7003

  Cryoprecipitate transfusion amount (mL)

18.28 (110.27)

14.69 (125.73)

0.6932

 Platelet transfusion

6 (6.00%)

2 (2.00%)

0.1493

  Platelet transfusion amount (mL)

16.46 (79.20)

3.02 (30.00)

0.1492

 Lactated ringers

99 (99.00%)

100 (100.00%)

0.9991

  Lactated ringers amount (mL)

3297.83 (1759.02)

2402.88 (771.84)

< 0.0012

 Saline

55 (55.00%)

23 (23.00%)

< 0.0013

  Saline amount (mL)

456.00 (612.34)

131.50 (298.54)

< 0.0012

 Hydroxyethyl starch 6%

38 (38.00%)

0 (0.00%)

< 0.0011

  Hydroxyethyl starch 6% amount (mL)

533.50 (869.00)

0.00 (0.00)

< 0.0012

 Albumin 5%

4 (4.00%)

67 (67.00%)

< 0.0011

  Albumin 5% amount (mL)

27.72 (164.11)

832.75 (761.88)

< 0.0012

 Total IV volume of colloids intraoperatively (mL)

1293.22 (1022.68)

1152.50 (689.19)

0.4602

 Total IV volume of crystalloids intraoperatively (mL)

3758.83 (1850.67)

2546.08 (827.96)

< 0.0012

 Day of surgery, fluids ≥1 L

40 (40.40%)

43 (43.00%)

0.7103

  1. Continuous variables reported as mean (sd); categorical variables reported as frequency (percentage)
  2. 1Fisher exact
  3. 2Wilcoxon
  4. 3Chi-square