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Table 2 Comorbidities of albumin-exposed and non-exposed patients before and after matching with respect to absolute standardized difference

From: Acute kidney injury in postoperative shock: is hyperoncotic albumin administration an unrecognized resuscitation risk factor?

Comorbidity, no. (%) All patients Matched patients
Albumin (N = 4669) Control (N = 6843) ASD* Albumin (N = 3600) Control (N = 3600) ASD*
Congestive heart failure 1985 (43) 1888 (28) 0.317 1397 (39) 1440 (40) 0.024
Vascular disease 2509 (54) 2571 (38) 0.329 1924 (53) 1974 (55) 0.028
Pulmonary circulation disease 454 (10) 457 (7) 0.111 293 (8) 294 (8) 0.001
Peripheral vascular disease 970 (21) 1094 (16) 0.124 682 (19) 654 (18) 0.020
Hypertension, uncomplicated 2960 (63) 3689 (54) 0.194 2232 (62) 2264 (63) 0.018
Hypertension, complicated 41 (1) 91 (1) 0.043 35 (1) 41 (1) 0.017
Paralysis 42 (1) 87 (1) 0.036 30 (1) 28 (1) 0.006
Chronic pulmonary disease 780 (17) 910 (13) 0.096 548 (15) 555 (15) 0.006
Diabetes w/o chronic complications 881 (19) 1152 (17) 0.053 671 (19) 673 (19) 0.001
Diabetes w/ chronic complications 112 (2) 159 (2) 0.005 86 (2) 91 (3) 0.009
Hypothyroidism 590 (13) 691 (10) 0.080 429 (12) 410 (11) 0.017
Renal failure 517 (11) 615 (9) 0.069 374 (10) 362 (10) 0.011
Liver disease 165 (4) 283 (4) 0.032 137 (4) 118 (3) 0.029
Peptic ulcer disease (non-bleeding) 0 (0) 2 (0) 0.025 0 (0) 1 (0) 0.025
Lymphoma 130 (3) 193 (3) 0.002 104 (3) 102 (3) 0.004
Metastatic cancer 49 (1) 74 (1) 0.003 32 (1) 25 (1) 0.023
Solid tumor w/out metastasis 451 (10) 637 (9) 0.012 324 (9) 317 (9) 0.007
Rheumatoid arthritis/collagen vas 102 (2) 167 (2) 0.017 86 (2) 82 (2) 0.007
Coagulopathy 1784 (38) 1570 (23) 0.336 1192 (33) 1145 (32) 0.028
Obesity 234 (5) 341 (5) 0.001 169 (5) 186 (5) 0.022
Weight loss 581 (12) 620 (9) 0.109 373 (10) 356 (10) 0.016
Fluid and electrolyte disorders 3282 (70) 3873 (57) 0.287 2481 (69) 2546 (71) 0.039
Chronic blood loss anemia 59 (1) 106 (2) 0.025 51 (1) 50 (1) 0.003
Deficiency anemias 911 (20) 1184 (17) 0.057 685 (19) 686 (19) 0.001
Alcohol abuse 84 (2) 123 (2) 0.000 61 (2) 75 (2) 0.029
Drug abuse 27 (1) 58 (1) 0.032 22 (1) 16 (0) 0.024
Psychoses 159 (3) 277 (4) 0.034 133 (4) 129 (4) 0.006
  1. *ASD absolute difference in means or proportions divided by the pooled standard deviation; imbalance was defined as an ASD greater than 0.046 (i.e., \( 1.96\times \sqrt{\frac{1}{3600}+\frac{1}{3600}} \))