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Table 1 Demographic and perioperative characteristics of albumin-exposed and non-exposed patients before and after matching with respect to absolute standardized difference

From: Acute kidney injury in postoperative shock: is hyperoncotic albumin administration an unrecognized resuscitation risk factor?

Variable

All patients

Matched patients

Albumin (N = 4669)

Control (N = 6843)

ASD*

Albumin (N = 3600)

Control (N = 3600)

ASD*

Age, years

67 ± 13

63 ± 15

0.238

66 ± 13

66 ± 13

0.015

Gender (male), no. (%)

2882 (62)

4203 (61)

0.006

2239 (62)

2269 (63)

0.017

Race

  

0.087

  

0.018

 Caucasian

4197 (90)

6000 (88)

 

3220 (89)

3239 (90)

 

 African American

256 (5)

522 (8)

 

198 (6)

185 (5)

 

 Others

216 (5)

321 (5)

 

182 (5)

176 (5)

 

Body mass index, kg/m2

28.4 ± 6.5

29.1 ± 7.0

0.108

28.6 ± 6.3

28.6 ± 6.3

0.014

ASA physical status, no. (%)

  

0.274

  

0.067

 I

18 (0)

46 (1)

 

11 (0)

5 (0)

 

 II

79 (2)

271 (4)

 

51 (1)

45 (1)

 

 III

985 (21)

2083 (30)

 

755 (21)

672 (19)

 

 IV

3587 (77)

4443 (65)

 

2783 (77)

2878 (80)

 

Emergent surgery, no. (%)

198 (4)

433 (6)

0.094

151 (4)

139 (4)

0.017

Type of surgery †, no. (%)

  

–

  

0.000

 Replacement of aortic valve

1318 (37.5)

1495 (37.3)

 

1120 (37.3)

1120 (37.3)

 

 CABG artery-vein single

750 (21.4)

714 (17.8)

 

621 (20.7)

621 (20.7)

 

 Replacement of mitral valve

420 (12.0)

448 (11.2)

 

391 (13.0)

391 (13.0)

 

 Repair of mitral valve

343 (9.8)

411 (10.3)

 

283 (9.4)

283 (9.4)

 

 Ascending aortic graft

287 (8.2)

234 (5.8)

 

225 (7.5)

225 (7.5)

 

 Revise ventricular muscle

108 (3.1)

201 (5.0)

 

96 (3.2)

96 (3.2)

 

 Transplantation of liver

75 (2.1)

192 (4.8)

 

73 (2.4)

73 (2.4)

 

 Exploration of abdomen

100 (2.9)

133 (3.3)

 

108 (3.6)

108 (3.6)

 

 Repair of mitral valve

84 (2.4)

74 (1.9)

 

61 (2.0)

61 (2.0)

 

 CABG arterial single

27 (0.8)

106 (2.6)

 

25 (0.8)

25 (0.8)

 

Duration of surgery, (h)

7.0 ± 2.4

6.5 ± 2.6

0.198

6.9 ± 2.1

6.8 ± 2.1

0.042

Intraoperative time-weighted average of MAP, mmHg

75.4 ± 6.6

77.4 ± 8.3

0.269

75.3 ± 6.1

75.1 ± 6.3

0.006

Use of hydroxyethyl starch, no. (%)

2326 (50)

3524 (52)

0.034

1854 (52)

2088 (58)

0.131

Use of furosemide, no. (%)

224 (5)

179 (3)

0.116

112 (3)

87 (2)

0.042

  1. ASA American Society of Anesthesiologist, ASD absolute standardized difference, MAP mean arterial blood pressure, TWA time-weighted average
  2. *ASD absolute difference in means or proportions divided by the pooled standard deviation; imbalance was defined as an ASD greater than 0.046 (i.e., \( 1.96\times \sqrt{\frac{1}{3600}+\frac{1}{3600}} \))
  3. †Ten most frequent procedures are listed