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Table 1 Opioid-reducing enhanced recovery pathway. This is the protocol used at the authors’ institution for multimodal, opioid-reducing analgesia

From: The rising tide of opioid use and abuse: the role of the anesthesiologist

 

Duration of surgery

 

Drug

Short (1–2 h)

Long (> 2 h)

Notes

Preoperative (day prior)

 Tylenol

975 mg TID

975 mg TID

 

 Ibuprofen

800 mg TID

800 mg TID

 

Holding room

 Gabapentin

600 mg

600 mg

 

 Celebrex

450 mg

450 mg

 

 Tylenol

975 mg

975 mg

 

 Glycopyrolate

0.2–0.3 mg

0.2–0.3 mg

 

Intraoperative

 Induction

  Ketamine

Bolus

Bolus and infusion

Bolus 0.25 mg/kg

Infusion 4 μg/kg/min

  Lidocaine

Bolus

Infusion

Bolus 1 mg/kg

Infusion 1 mg/kg/h

  Dexmetatomidine

 

Bolus and infusion

Bolus 1 μg/kg

Infusion 0.1 μg/kg/h

  Magnesium

Bolus

Bolus and infusion

Bolus 2 g

Infusion 1 g/h

 Analgesics (provider discretion)

  Toradol

Bolus

Bolus

15–30 mg

  Hydromorphone

Bolus

Bolus

0.2–0.4 mg

  Morphine

Bolus

Bolus

0.06–0.1 mg/kg

PACU

 Analgesics

   

  Fentanyl

25 μg/dose

25 μg/dose

 

  Hydromorphone

0.2–0.4 mg/dose

0.2–0.4 mg/dose

 

  Morphine

4 mg/dose

4 mg/dose

 

 Antiemetics

  Zofran

4 mg

4 mg

 

  Dexamethasone

4–8 mg

4–8 mg

 

  Haldol

1–2 mg

1–2 mg

 

  Benadryl

6.25 mg

6.25 mg

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