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Table 2 Unadjusted renal outcomes in patients treated with ERP vs. traditional care

From: Enhanced recovery protocols for colorectal surgery and postoperative renal function: a retrospective review

 

Control (N = 464)

ERP (N = 590)

All patients (N = 1054)

p value

Preoperative creatinine (mg/dL, median [IQR])

0.9 (0.8–1.1)

0.9 (0.7–1.0)

0.9 (0.8–1.1)

0.002

Max postoperative creatinine (mg/dL, median [IQR])

1.0 (0.8–1.2)

1.0 (0.8–1.2)

1.0 (0.8–1.2)

0.008

Creatinine differences (mg/dL)

0.0 (0.0–0.1)

0.1 (0.0–0.3)

0.1 (0.0–0.2)

< 0.001

Level of postoperative kidney injury

   

0.998

No kidney injury

95.5% (443)

95.4% (563)

95.4% (1006)

 

Acute kidney injury (2× increase)

3.7% (17)

3.7% (22)

3.7% (39)

 

Acute kidney failure (3× increase)

0.9% (4)

0.8% (5)

0.9% (9)

 
  1. Acute kidney injury and failure thresholds set at 2× and 3× increase in creatinine, based on RIFLE criteria cutoffs. Wilcoxon rank-sum test was used to compare creatinine ranges; Mann–Whitney U test was used to compare incidences of kidney injury and failure
  2. ERP enhanced recovery protocol, IQR interquartile range