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Table 3 Univariate analysis: tier 1 and 2 predictors of C-POMS summary score on D3, D5 and D8

From: Predictors of total morbidity burden on days 3, 5 and 8 after cardiac surgery

Variable D3 (n = 441) D5 (n = 419) D8 (n = 177)
Median C-POMS/Rho p Median C-POMS/Rho p Median C-POMS/Rho p
Tier 1 variables
Demographics
Age 0.188 0.000 0.110 0.025 0.133 0.078
Age quartiles
 1 (0–59) 2.0 0.002 2.0 0.010 2.0 0.300
 2 (60–68) 3.0 2.0 3.0
 3 (69–74) 3.0 2.0 4.0
 4 (≥75) 4.0 2.5 3.0
Age grp 2
 <65 2.0 0.000 2.0 0.044 2.5 0.083
 65–74 3.0 2.0 3.0
 ≥75 4.0 2.5 3.0
Age grp 3
 <70 3.0 0.001 2.0 0.426 3.0 0.225
 70–79 3.0 2.0 3.0
 >80 5.0 2.0 3.0
Gender
 M 3.0 0.024 2.0 0.016 3.0 0.215
 F 3.0 3.0 2.5
Medical history
Diabetes
 Y 4.0 0.000 2.5 0.015 3.0 0.308
 N 3.0 2.0 3.0
Cerebrovascular disease
 Y 4.0 0.028 3.0 0.023 4.0 0.219
 N 3.0 2.0 3.0
Neurological history
 Y 4.0 0.103 3.0 0.016 4.0 0.553
 N 3.0 2.0 3.0
Congestive heart failure
 Y 4.0 0.009 4.0 0.025 4.0 0.310
 N 3.0 2.0 3.0
COPD/lung disease
 Y 4.0 0.005 3.0 0.012 3.0 0.380
 N 3.0 2.0 3.0
Renal disease
 Y 5.0 0.064 5.0 0.001 5.0 0.025
 N 3.0 2.0 3.0
POSSUM ECG
 Normal 3.0 0.000 2.0 0.000 3.0 0.200
 Sinus abnormal 5.0 4.0
 AF 4.0 3.0 3.0
 Any other abnormal 5.0 2.5 2.0
Paced
 Y 5.0 0.005 4.0 0.014 2.5 0.875
 N 3.0 2.0 3.0
Dialysis
 Y 5.5 0.073 7.5 0.006 5.5 0.064
 N 3.0 2.0 3.0
Pre-operative measurements
Body mass index(kg/m2) 0.100 0.043 0.077 0.130 0.099 0.206
 LVEF
 Good 3.0 0.013 2.0 0.011 3.0 0.013
 Fair 3.0 2.0 4.0
 Poor 5.0 5.0 4.0
Intra-operative
Type of surgery
 CABG 3.0 0.000 2.0 0.000 3.0 0.718
 AVR 4.0 3.0 3.0
 MVR 5.0 3.0 3.5
 CABG + AVR 4.0 2.0 3.0
 AVR + MVR 3.0 3.0 4.5
 CABG + MVR + AVR 5.0 5.0 6.0
 Other 5.0 3.0 3.0
Urgency of op
 Elective 3.0 0.002 2.0 0.061 3.0 0.327
 Urgent 4.0 2.0 3.0
Within first 12 h
Systolic blood pressure (highest) 0.002 0.959 0.026 0.599 −0.089 0.238
Tier 2 variables
Demographics
Ethnicity
 Caucasian 3.0 0.052 2.0 0.008 3.0 0.532
 Asian 2.0 1.0 3.0
 Black 5.0 3.0 3.0
 Other 2.0 3.0 1.0
Medical history
 Smoking
 Current 2.0 0.048 2.0 0.395 3.0 0.753
 Ex 3.0 2.0 3.0
 Never 3.0 2.0 3.0
Family Hx CAD
 Y 3.0 0.002 2.0 0.019 3.0 0.686
 N 4.0 2.0 3.0
Atrial arrhythmia
 Y 4.0 0.021 3.0 0.007 3.0 0.781
 N 3.0 2.0 3.0
Pre-operative measurements
 Albumin −0.210 0.000 −0.144 0.004 −0.183 0.019
 Haemoglobin −0.279 0.000 −0.180 0.000 −0.143 0.058
 Heart rate 0.090 0.058 0.179 0.000 0.080 0.294
 Weight 0.044 0.369 0.042 0.399 0.101 0.186
No diseased vessels       
 0 4.0 0.011 3.0 0.000 3.0 0.203
 1 3.0 2.0 2.0
 2 3.0 2.0 2.0
 3 3.0 2.0 3.0
NYHA class
 1 2.0 0.001 1.0 0.002 3.0 0.001
 2 3.0 2.0 3.0
 3 4.0 3.0 3.0
 4 5.0 2.5 5.0
CCSC class
 0 3.0 0.041 3.0 0.042 3.0 0.317
 1 2.0 2.0 2.0
 2 3.0 2.0 3.0
 3 3.0 2.0 3.0
 4 4.0 2.0 4.0
Cardiomegaly
 Y 5.0 0.000 3.0 0.000 4.0 0.141
 N 3.0 3.0 3.0
 Not stated 3.0 3.0 3.0
Extracardiacarteriopathy
 Y 5.0 0.003 3.0 0.004 4.5 0.147
 N 3.0 2.0 3.0
Current medications
Diuretic
 Y 4.0 0.003 3.0 0.003 3.0 0.780
 N 3.0 2.0 3.0
Intra-operative
Cardiopulmonary bypass
 Y 3.0 0.001 2.0 0.072 3.0 0.098
 N 2.0 1.0 1.0
Within 1st 12 h after surgery
 Total drainage 0.139 0.004 0.030 0.542 0.031 0.679
Post-operative (D1)
Heart rhythm
 Sinus rhythm 3.0 0.000 2.0 0.002 3.0 0.473
 Sinus tachycardia 2.5 2.0 2.5
 Sinus bradycardia 4.0 2.0 4.0
 Atrial fibrillation 5.0 3.0 4.0
 Other 3.0 2.0 3.0
Inotropes
 Y 4.0 0.004 3.0 0.070 3.0 0.923
 N 3.0 2.0 3.0