Table 1 Baseline characteristics of patients recruited to the OPTIMISE trial
| Â | Peri-operative cardiac output-guided haemodynamic therapy algorithm | Usual care |
|---|---|---|
(n = 368) | (n = 365) | |
Age (year) | 71.26 (8.4) | 72.20 (8.6) |
Gender, male | 237 (64.4) | 229 (62.7) |
Urgency of surgery | Â | Â |
 Elective surgery | 356 (96.7) | 352 (96.4) |
 Non-elective surgery | 12 (3.3) | 13 (3.6) |
Surgery†|  |  |
 Upper gastrointestinal | 108 (29.4) | 111 (30.4) |
 Lower gastrointestinal | 168 (45.7) | 165 (45.2) |
 Small bowel +/− pancreas | 86 (23.4) | 82 (22.5) |
 Urological or gynaecological involving gut | 5 (1.4) | 4 (1.1) |
 No surgery performed | 1 (0.3) | 3 (0.8) |
ASA gradea | Â | Â |
 1 | 22 (6.0) | 27 (7.4) |
 2 | 200 (54.4) | 174 (47.7) |
 3 | 143 (38.9) | 155 (42.5) |
 4 | 3 (0.8) | 9 (2.5) |
Location following surgery | Â | Â |
 Critical care level 2 | 258 (70.1) | 246 (67.4) |
 Critical care level 3 | 42 (11.4) | 40 (11.0) |
 Post-anaesthetic recovery unit | 10 (2.7) | 9 (2.5) |
 General ward | 58 (15.8) | 70 (19.2) |
Renal impairment | 26 (7.1) | 12 (3.3) |
Diabetes mellitus | 57 (15.5) | 65 (17.8) |
Risk factor for cardiac or respiratory disease | 118 (32.1) | 118 (32.3) |
Baseline quality of life scorea | 0.78 (0.2) | 0.77 (0.3) |