Perioperative fluid therapy: a statement from the international Fluid Optimization Group

Table 3 Main current concerns regarding the use of specific crystalloids and colloids

Solution	Concerns	Literature
Normal saline	Hyperchloremic acidosis	Hyperchloremia after noncardiac surgery is independently associated with morbidity and mortality [108]
Normal saline	Reduction of renal perfusion	May contribute to acute renal injury [109,110]
Starch solutions	Acute kidney injury and increased requirement of renal replacement therapy	Critically ill septic patients [111-114]
	Increased mortality	Critically ill septic patients [112,114]
	Increased need for PRBC transfusion	Critically ill septic patients [114]

Results of clinical trials comparing fluid resuscitation with colloids and crystalloids in different populations have been conflicting. This table summarizes current concerns regarding specific crystalloids and colloids.

ISSN: 2047-0525