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Table 5 Direct fluid acquisition costs in the Hextend® and Voluven® groups

From: Perioperative clinical and economic outcomes associated with replacing first-generation high molecular weight hydroxyethyl starch (Hextend®) with low molecular weight hydroxyethyl starch (Voluven®) at a large medical center

  2009 ( n= 2,098) 2010 ( n= 2,790) P value
Total N Mean SD Total N Mean SD
Hextend units cost 2,098 $55.13 $27.80 2,790 $0.00 $0.00 <0.0001
Voluven units cost 2,098 $0.00 $0.00 2,790 $116.01 $65.05
Plasmanate units cost 2,098 $8.07 $29.85 2,790 $0.85 $9.21 <0.0001
LR units cost 1,977 $4.84 $2.93 2,774 $4.31 $2.52 <0.0001
NS units cost 1,977 $0.60 $1.49 2,774 $0.64 $1.53 0.196
Colloids (Hex/Vol + Plas) cost 2,098 $63.20 $33.53 2,790 $116.87 $64.80 <0.0001
All fluids units cost (observed) 1,977 $68.03 $33.22 2,774 $122.10 $65.85 <0.0001
All fluids units cost (imputed) 2,098 $68.65 $34.68 2,790 $121.82 $65.82  
  1. Cost ($) statistics include all cases (none given = $0). ml, milliliters; LR, lactated Ringer’s; NS, normal saline; SD, standard deviation.