Choice of anesthetic technique on plasma concentrations of interleukins and cell adhesion molecules

Table 3 Area under the curve between-group comparisons

	Total intravenous anesthesia (n= 44)	Isoflurane (n= 44)	P value
IL-1β (pg·hour/ml)	3.4 (3.0 to 4.3)	3.3 (2.9 to 4.0)	0.428
IL-6 (pg·hour/ml)	33.0 (21.6 to 44.9)	78.0 (52.2 to 109.1)	0.006
IL-8 (pg·hour/ml)	49.0 (39.6 to 67.0)	54.0(47.2 to 82.6)	0.285
IL-10 (pg·hour/ml)	37.0 (23.8 to 55.4)	26.0 (21.6 to 42.1)	0.151
IL-13 (pg·hour/ml)	93.0 (83.4 to 101.3)	101.0 (89.8 to 112.1)	0.218
Soluble ICAM-1(ng·hour/ml)	213 (188.0 to 242.3)	197 (178.9 to 220.9)	0.488
Soluble VCAM-1(ng·hour/ml)	1,139 (1,029 to 1,188)	1,029 (947 to 1,163)	0.226

Data expressed as median (95% confidence interval). Area-under-the-curve based on preoperative values. Mann–Whitney U tests were used for between-group comparisons; because multiple comparisons were made, P<0.01 was considered statistically significant. Bold data are significant.

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