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Table 1 Classification of acute kidney injury by RIFLE, AKIN and KIDGO criteria[12, 28, 36]

From: Perioperative acute kidney injury

Stage Glomerular filtration rate (GFR) criteria Urine output criteria
RIFLE classification   
Risk Serum creatinine increased x 1.5 or GFR decrease >25% <0.5 ml/kg/hr for ≥ 6 hours
Injury Serum creatinine increased x 2 or GFR decrease >50% <0.5 ml/kg/hr for ≥ 12 hours
Failure Serum creatinine increased x 3 or GFR decrease ≥ 75% or an absolute serum creatinine ≥ 354 μmol/L with an acute rise ≥ 4 μmol/L <0.3 ml/kg/hr for ≥ 24 hours or anuria for ≥12 hours
Loss Persistent AKI, requiring RRT for > 4 weeks  
End-stage kidney disease Requiring dialysis > 3 months  
AKIN classification   
Stage 1 Serum creatinine increased ≥26.2 μmol/L or x 0.5 to 2 baseline <0.5 ml/kg/hr for ≥ 6hours
Stage 2 Serum creatinine increased x 2 to 3 baseline <0.5 ml/kg/hr for ≥ 12 hours
Stage 3 Serum creatinine increased > x 3 baseline or serum creatinine ≥ 354 μmol/L with an acute rise ≥ 44 μmol/L or initiation of RRT <0.3 ml/kg/hr for ≥ 24 hours or anuria for ≥12 hours
KDIGO classification   
Stage 1 Serum creatinine increased x 1.5 to 1.9 baseline or by ≥ 26.2 μmol/L <0.5 ml/kg/hr for 6 to 12 hours
Stage 2 Serum creatinine increased x 2 to 2.9 baseline <0.5 ml/kg/hr for ≥ 12 hours
Stage 3 Serum creatinine increased > x 3 baseline or serum creatinine ≥ 354 μmol/L with an acute rise ≥ 44 μmol/L or initiation of RRT <0.3 ml/kg/hr for ≥ 24 hours or anuria for ≥12 hours
  1. AKIN, Acute Kidney Injury Network; KDIGO, Kidney Disease: Improving Global Outcomes.