Table 1 Classification of acute kidney injury by RIFLE, AKIN and KIDGO criteria[12, 28, 36]
Stage | Glomerular filtration rate (GFR) criteria | Urine output criteria |
|---|---|---|
RIFLE classification | Â | Â |
Risk | Serum creatinine increased x 1.5 or GFR decrease >25% | <0.5 ml/kg/hr for ≥ 6 hours |
Injury | Serum creatinine increased x 2 or GFR decrease >50% | <0.5 ml/kg/hr for ≥ 12 hours |
Failure | Serum creatinine increased x 3 or GFR decrease ≥ 75% or an absolute serum creatinine ≥ 354 μmol/L with an acute rise ≥ 4 μmol/L | <0.3 ml/kg/hr for ≥ 24 hours or anuria for ≥12 hours |
Loss | Persistent AKI, requiring RRT for > 4 weeks |  |
End-stage kidney disease | Requiring dialysis > 3 months |  |
AKIN classification | Â | Â |
Stage 1 | Serum creatinine increased ≥26.2 μmol/L or x 0.5 to 2 baseline | <0.5 ml/kg/hr for ≥ 6hours |
Stage 2 | Serum creatinine increased x 2 to 3 baseline | <0.5 ml/kg/hr for ≥ 12 hours |
Stage 3 | Serum creatinine increased > x 3 baseline or serum creatinine ≥ 354 μmol/L with an acute rise ≥ 44 μmol/L or initiation of RRT | <0.3 ml/kg/hr for ≥ 24 hours or anuria for ≥12 hours |
KDIGO classification | Â | Â |
Stage 1 | Serum creatinine increased x 1.5 to 1.9 baseline or by ≥ 26.2 μmol/L | <0.5 ml/kg/hr for 6 to 12 hours |
Stage 2 | Serum creatinine increased x 2 to 2.9 baseline | <0.5 ml/kg/hr for ≥ 12 hours |
Stage 3 | Serum creatinine increased > x 3 baseline or serum creatinine ≥ 354 μmol/L with an acute rise ≥ 44 μmol/L or initiation of RRT | <0.3 ml/kg/hr for ≥ 24 hours or anuria for ≥12 hours |